Anitha Thampi was born in a rural area of Central Kerala to a progressive family in 1968 and grew up as the eldest among three sisters. According to Thampi, she grew up watching her green rural expanse slowly turning into a crowded town, which had an immense influence on her poetry. She became a chemical engineer in professional capacity who later delved into the literary world of poetry. Thampi published her first book, Muttamatikkumpol (While Sweeping the Front Yard) in 2004. The book was accorded with the title of "the best poetry book of the year" by Mathrubhumi. The paper also described her style to have a post-modernist approach. In 2007, she translated the works of the Australian poet Les Murray into Malayalam and compiled them in a collection called Kavithakal. She published her second book, Azhakillathavayellam (All that are bereft of beauty) in 2010 and her third book, Alappuzha Vellam (Alappuzha Water) in 2016.